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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
17.58
Human Site:
S246
Identified Species:
27.62
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S246
G
R
P
G
G
E
G
S
P
S
P
K
T
R
E
Chimpanzee
Pan troglodytes
XP_510301
627
67581
S225
S
L
V
A
K
A
Q
S
L
P
S
D
Q
P
V
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S246
G
R
P
G
G
E
G
S
P
S
P
K
T
Q
E
Dog
Lupus familis
XP_544614
968
105825
S533
G
R
P
G
G
E
G
S
P
S
P
K
T
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S247
G
R
P
G
G
E
G
S
P
S
P
K
N
Q
E
Rat
Rattus norvegicus
Q62829
544
60692
S142
Q
K
Y
M
S
F
T
S
G
D
K
S
A
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
S237
S
S
Q
A
R
D
S
S
L
K
R
R
L
F
C
Chicken
Gallus gallus
XP_426393
667
74767
E246
S
P
S
S
K
S
R
E
N
S
L
K
R
R
L
Frog
Xenopus laevis
NP_001082100
650
73749
R241
P
Q
S
P
R
D
K
R
P
L
S
G
P
N
I
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
F246
N
P
R
P
I
T
C
F
Y
S
P
T
Q
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q237
G
G
S
M
P
Q
Q
Q
Q
T
S
P
V
G
S
Honey Bee
Apis mellifera
XP_001122147
624
70155
S222
P
I
N
T
P
Q
C
S
I
Q
S
P
S
T
P
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
I170
L
P
Y
H
G
N
K
I
Q
D
P
R
K
M
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T397
V
K
F
Y
Q
D
V
T
E
T
N
G
E
D
K
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
E395
T
F
Y
K
E
T
T
E
K
P
Q
E
D
Q
Q
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
86.6
6.6
N.A.
6.6
20
6.6
13.3
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
13.3
N.A.
20
20
20
13.3
N.A.
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
0
7
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
20
0
0
0
14
0
7
7
7
0
% D
% Glu:
0
0
0
0
7
27
0
14
7
0
0
7
7
0
27
% E
% Phe:
0
7
7
0
0
7
0
7
0
0
0
0
0
7
0
% F
% Gly:
34
7
0
27
34
0
27
0
7
0
0
14
0
7
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
7
0
0
7
7
0
0
0
0
0
7
% I
% Lys:
0
14
0
7
14
0
14
0
7
7
7
34
7
0
7
% K
% Leu:
7
7
0
0
0
0
0
0
14
7
7
0
7
0
7
% L
% Met:
0
0
0
14
0
0
0
0
0
0
0
0
0
14
0
% M
% Asn:
7
0
7
0
0
7
0
0
7
0
7
0
7
7
7
% N
% Pro:
14
20
27
14
14
0
0
0
34
14
40
14
7
7
14
% P
% Gln:
7
7
7
0
7
14
14
7
14
7
7
0
14
27
7
% Q
% Arg:
0
27
7
0
14
0
7
7
0
0
7
14
7
14
0
% R
% Ser:
20
7
20
7
7
7
7
54
0
40
27
7
7
0
7
% S
% Thr:
7
0
0
7
0
14
14
7
0
14
0
7
20
7
0
% T
% Val:
7
0
7
0
0
0
7
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
7
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _